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Related Concept Videos

Interpreting R Charts01:22

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R chart, or range chart, is a fundamental tool in statistical process control used to monitor the variability within a process. It complements the X-bar (x̄) chart by focusing on the range of the data, rather than individual values, providing a clear picture of the process dispersion over time.
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An unknown compound can be established by identifying the molecular ion peak in the mass spectrum. The molecular ion peak is often weak or absent due to the predominance of fragmentation in high-energy electron beams. In such cases, a soft-energy electron beam can be used to scan the spectrum to enhance the intensity of the molecular ion peak. Additionally, chemical ionization, field ionization, and desorption ionization spectra are used to obtain a relatively intense molecular ion peak.To...
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Bile Salt-induced Biofilm Formation in Enteric Pathogens: Techniques for Identification and Quantification
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Diagnostic Interpretation Guidance for Pediatric Enteric Pathogens: A Modified Delphi Consensus Process.

Antonia S Stang1, Melanie Trudeau2, Otto G Vanderkooi3

  • 1Departments of Pediatrics, Emergency Medicine and Community Health Sciences, University of Calgary, Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada.

The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale
|October 27, 2018
PubMed
Summary
This summary is machine-generated.

Diagnostic test guidance definitions were developed for 17 pediatric enteric pathogens. Further research is needed for two specific pathogens to refine diagnostic criteria.

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Area of Science:

  • Medical Diagnostics
  • Infectious Diseases
  • Microbiology

Background:

  • Pediatric enteric infections pose diagnostic challenges.
  • Multianalyte molecular platforms complicate test result interpretation.
  • Need for standardized diagnostic test guidance definitions.

Purpose of the Study:

  • Develop diagnostic test guidance definitions for pediatric enteric infections.
  • Facilitate interpretation of positive results from molecular diagnostic platforms.

Main Methods:

  • Systematic, two-phase, modified Delphi consensus process.
  • Web-based surveys and an expert panel face-to-face meeting.
  • Expert panel rated pathogen definitions for likelihood of causing illness.

Main Results:

  • 19 pathogens identified for definition development.
  • 13 definitions achieved high agreement (≥67%) in initial expert survey.
  • Two definitions (Clostridium difficile, Entamoeba histolytica/dispar) required modification after expert meeting.

Conclusions:

  • Developed diagnostic test guidance definitions for 17 enteric pathogens.
  • Provided tools for healthcare providers interpreting test results.
  • Identified two pathogens needing further research and definition development.