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Related Concept Videos

Veins01:17

Veins

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Veins are an integral part of our circulatory system, serving as the blood vessels that transport blood from all body regions to the heart. They are a network of hollow tubes that carry blood low in oxygen from the body's cells back to the heart for reoxygenation. Veins are crucial for maintaining the body's overall fluid balance and the continuous circulation of blood.
Structure of Veins:
The structure of veins is specifically designed to assist in the low-pressure transportation of...
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Veins of Thorax01:19

Veins of Thorax

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The azygos system is a crucial part of the body's circulatory system and drains most of the thorax. It comprises the azygos, hemiazygos, and accessory hemiazygos veins.
The azygos vein, positioned just right of the midline and anterior to the vertebral column, begins at the junction of the right ascending lumbar and subcostal veins, terminating in the superior vena cava. This vein drains blood from the right side of the thoracic wall, thoracic viscera, and posterior abdominal wall.
The...
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Veins of Lower Limbs01:15

Veins of Lower Limbs

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The human body consists of an intricate network of veins responsible for the crucial task of blood drainage from the lower limbs. These veins can be categorized into two main types: deep veins and superficial veins.
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the...
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Veins as Blood Reservoirs01:10

Veins as Blood Reservoirs

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Veins, while chiefly responsible for circulating blood back to the heart, also function as storage vessels for blood. They house approximately 64 percent of the body's total blood volume, a feat made possible by their high capacitance—the inherent ability to expand and accommodate large volumes of blood, even under low pressure. The large diameter and thin walls of veins augment their distensibility, significantly more so than arteries, due to their classification as capacitance...
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Overview of Systemic Veins01:11

Overview of Systemic Veins

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Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...
1.2K
Veins of the Abdomen and Pelvis01:18

Veins of the Abdomen and Pelvis

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The human body is a complex system of interconnected parts, and the circulatory system plays a crucial role in maintaining overall health. One key component of this system is the inferior vena cava, a large vein responsible for returning blood from the abdominopelvic viscera and abdominal walls to the heart.
The inferior vena cava is fed by numerous smaller veins. The lumbar veins, for instance, drain the posterior abdominal wall, emptying both directly into the inferior vena cava and into the...
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Choroid changes in vortex vein-occluded monkeys.

Lu-Lu Chen1, Qiong Wang2, Wei-Hong Yu1

  • 1Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.

International Journal of Ophthalmology
|October 27, 2018
PubMed
Summary
This summary is machine-generated.

Vortex vein occlusion in monkeys causes acute hemodynamic and structural changes in the choroid. Long-term effects appear minimal, suggesting autoregulation plays a key role in choroidal vascular recovery.

Keywords:
choroidal circulatory disturbancecynomolgus monkeyvortex vein occlusion

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Area of Science:

  • Ophthalmology
  • Vascular Biology
  • Primate Research

Background:

  • Vortex veins are crucial for choroidal circulation.
  • Understanding choroidal vascular changes is vital for treating eye diseases.

Purpose of the Study:

  • To investigate acute and chronic choroidal vascular alterations following vortex vein occlusion in a primate model.

Main Methods:

  • Temporal vortex veins in cynomolgus monkeys were occluded.
  • Fluorescein angiography (FA), indocyanine green angiogram (ICGA), and enhanced-depth imaging optical coherence tomography (EDI-OCT) were utilized.
  • Choroid vascular index (CVI) was calculated from EDI-OCT images.

Main Results:

  • Occlusion of two vortex veins led to delayed choroidal artery filling and increased choroidal thickness.
  • Choroidal vascular index changes were observed in specific quadrants.
  • Occlusion of a single vortex vein had minimal impact.

Conclusions:

  • Bilateral vortex vein occlusion induces acute hemodynamic and structural changes in the choroid.
  • Choroidal autoregulation appears to be the primary mechanism for long-term stability.
  • Monocular occlusion has limited effects on choroidal vascular status.