Related Experiment Video
Updated: Feb 3, 2026

In vivo Evaluation of Mucociliary Clearance in Mice
Published on: December 18, 2020
Effect of intermittent inspiratory leaks on measurement of lung clearance index using nitrogen and sulfur
Carl A Whitfield1,2, Oliver E Jensen2, Alex Horsley1
1Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK.
Abstract:
Even small air leaks can have a significant impact on LCI measured using N2. This is particularly the case for leaks that occur towards the end of washout. In contrast, leaks generally have a much smaller impact on LCI measured by SF6. http://ow.ly/az7b30lG5Ku.
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