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Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
14:05

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes

Published on: September 19, 2013

10.4K

[Spontaneous bacterial peritonitis caused by Listeria monocytogenes: eight case reports (1992-2017) and literature

M Fernández Torres1, I Angulo López, P Ruiz Bueno

  • 1Marina Fernández Torres. Servicio de Microbiología, Hospital Universitario Marqués de Valdecilla, Avda. Valdecilla 25, 39008 Santander, Cantabria. Spain. marina.f.torres@outlook.com.

Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia
|October 27, 2018
PubMed
Abstract

Insights

Listeria monocytogenes is a rare cause of spontaneous bacterial peritonitis (SBP) in patients with liver disease. Early diagnosis and specific antibiotic treatment are crucial for favorable outcomes, as conventional empirical therapies may be ineffective.

Area of Science:

  • Infectious Diseases
  • Hepatology
  • Microbiology

Background:

  • Spontaneous bacterial peritonitis (SBP) is a common complication in patients with cirrhosis.
  • Listeria monocytogenes is an uncommon pathogen identified in SBP cases.

Purpose of the Study:

  • To analyze cases of Listeria monocytogenes SBP over 26 years.
  • To highlight the importance of considering L. monocytogenes in SBP diagnosis.

Main Methods:

  • Descriptive analysis of L. monocytogenes SBP cases.
  • Review of patient demographics, clinical course, and treatment.

Main Results:

  • Eight patients diagnosed with L. monocytogenes SBP.
  • Half had underlying liver disease; others had malignancies, dialysis, or heart disease.
  • Five patients (62.5%) had favorable outcomes with directed antibiotics; three died.

Conclusions:

  • L. monocytogenes should be considered in SBP, especially in patients with liver disease.
  • Specific antibiotic treatment is necessary, differing from empirical therapies.
  • Early diagnosis and targeted treatment improve patient survival.

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