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Updated: Feb 3, 2026
11:39
Using Unfixed, Frozen Tissues to Study Natural Mucin Distribution
Published on: September 21, 2012
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Multicentric Mucinous Adenocarcinoma in the Periorbital Region
Meredith Furst1, Marie B Somogyi2, Ivan Vrcek2
1Long School of Medicine, University of Texas Health at San Antonio, San Antonio, Texas, U.S.A.
Ophthalmic Plastic and Reconstructive Surgery
|October 27, 2018
Summary
This case report details a rare multicentric primary mucinous adenocarcinoma of the skin in a 70-year-old woman. Successful surgical repair restored vision and eyelid function with no recurrence.
Area of Science:
- Dermatology
- Oncology
- Ophthalmology
Background:
- Primary mucinous adenocarcinoma of the skin is rare.
- Multicentric presentation is exceptionally uncommon.
Observation:
- A 70-year-old woman presented with two distinct skin lesions on her right eyelid and cheek.
- Immunohistochemical staining and imaging were used to differentiate primary skin cancer from metastatic disease.
Findings:
- The lesions were confirmed as primary mucinous adenocarcinoma of the skin.
- Surgical excision and reconstruction with a tarsoconjunctival flap and cheek flap were performed.
- The patient achieved full visual recovery and maintained excellent eyelid aesthetics post-surgery.
Implications:
- This case highlights the importance of considering primary skin malignancies even with multiple lesions.
- Successful surgical management can yield favorable cosmetic and functional outcomes.
- Further research may clarify the etiology and optimal management of multicentric cutaneous mucinous adenocarcinoma.
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