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Updated: Feb 3, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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Cathepsin S in the spinal microglia facilitates morphine-induced antinociceptive tolerance in rats

Li Xiao1, Xue Han2, Xiao-E Wang1

  • 1Department of Anesthesiology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510000, China.

Neuroscience Letters
|October 27, 2018
PubMed

Keywords:
Cathepsin SMicrogliaMinocyclineMorphine tolerancep38 MAPK

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