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Breast tuberculosis cases rising in Sicily.

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Mammary tuberculosis (TM) is a rare breast condition, particularly in non-endemic regions. Early diagnosis is crucial, especially in patients with HIV, to differentiate it from breast cancer.

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Case reportsExtra-pulmonary localizationFine nipple aspirationGranulomatous mastitisScrofolaTuberculosis

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Area of Science:

  • Oncology
  • Infectious Diseases
  • Radiology

Background:

  • Mammary tuberculosis (TM) is a rare breast condition, accounting for 0.1% of histological breast lesions.
  • Incidence is higher (3-4%) in endemic regions like India and Africa.
  • TM poses diagnostic challenges in radiological and microbiological investigations.

Purpose of the Study:

  • To highlight the diagnostic challenges of mammary tuberculosis.
  • To emphasize the importance of considering TM in the differential diagnosis of breast masses.
  • To underscore the need for increased awareness in regions with immigrant populations.

Main Methods:

  • Case report of a 26-year-old Eritrean female with HIV presenting with a large breast mass.
  • Clinical examination revealed a 12x10 cm tender right breast mass.
  • Fine needle aspiration (FNA) of the mass yielded milky and greenish fluid.

Main Results:

  • The patient presented with generalized lymphadenopathy and weakness.
  • The breast mass was large, tender, and involved the entire right breast.
  • FNA fluid characteristics were noted.

Conclusions:

  • The differential diagnosis between breast cancer and mammary tuberculosis is critical.
  • Increased immigration necessitates reconsidering tuberculosis in differential diagnoses, particularly in regions like Sicily.
  • Physicians must maintain a high index of suspicion for TM in relevant patient populations.