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Wound Healing Properties of Selected Natural Products

Nurul 'Izzah Ibrahim1, Sok Kuan Wong2, Isa Naina Mohamed3

  • 1Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia. nurulizzah88@gmail.com.

International Journal of Environmental Research and Public Health
|October 28, 2018
PubMed

Insights

Natural products accelerate wound healing by leveraging anti-inflammatory, antioxidant, and antibacterial properties. This review examines studies on natural compounds and their mechanisms in promoting tissue repair.

Area of Science:

  • Biomedical Science
  • Pharmacology
  • Natural Product Chemistry

Background:

  • Wound healing is a complex biological process essential for tissue repair.
  • Disruptions in healing can lead to prolonged damage and complications.
  • Factors like infections and diseases impair the natural healing cascade.

Purpose of the Study:

  • To review scientific literature on natural products for wound healing.
  • To explore the mechanisms by which natural products promote tissue repair.
  • To highlight in vitro, in vivo, and clinical evidence supporting their efficacy.

Main Methods:

  • Literature search for studies on natural products and wound healing.
  • Analysis of in vitro, in vivo, and clinical trial data.
  • Investigation of phytochemical constituents and their biological activities.

Main Results:

  • Natural products exhibit anti-inflammatory, antioxidant, and antibacterial effects.
  • Phytochemicals like flavonoids and tannins contribute to pro-collagen synthesis.
  • Selected natural products demonstrate significant wound healing promotion across study types.

Conclusions:

  • Natural products offer a promising therapeutic avenue for wound healing.
  • Bioactive compounds in botanicals are key to their efficacy.
  • Further research into mechanisms can optimize natural product-based wound therapies.
Keywords:
anti-inflammatoryantibacterialantioxidantcollagenpolyphenolsskin

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