Related Experiment Video
Updated: Feb 3, 2026

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses
Published on: February 3, 2022
Micro-planning for immunization in Kaduna State, Nigeria: Lessons learnt, 2017
Gregory C Umeh1, Dauda M Madubu1, Charles Korir1
1World Health Organization, Nigeria.
Insights
Overestimated denominators in polio campaigns inflate target populations. Household micro-planning with technology validation can improve immunization planning and evaluation in Nigeria.
Area of Science:
- Public Health
- Epidemiology
- Health Services Research
Background:
- Low Oral Polio Vaccine (OPV) 3 coverage in Kaduna State, Nigeria, necessitated increased supplemental OPV campaigns by the Global Polio Eradication Initiatives (GPEI).
- High-risk areas with low vaccine uptake and high refusal rates in Northern Nigeria experienced overestimated denominators for OPV campaigns, using the highest vaccination numbers as targets.
- This practice leads to inefficiencies and resource misallocation in polio eradication efforts.
Purpose of the Study:
- To assess the impact of overestimated denominators on immunization services in Kaduna State, Nigeria.
- To identify solutions for improving immunization planning, delivery, and performance evaluation.
- To address challenges in setting accurate target populations for vaccination campaigns.
Main Methods:
- A cross-sectional study was conducted in Kaduna State, Nigeria.
- Descriptive and quantitative approaches were employed, including household enumeration.
- Target populations for routine immunization (<1 year), polio campaigns (<5 years), and acute flaccid paralysis surveillance (<15 years) were determined.
Main Results:
- Significant differences were found between micro-planning and supplemental vaccination data for the <5 years population (p<0.05).
- Significant discrepancies were also observed between micro-planning and projected census data for the <1 year population (p<0.05).
- These findings highlight substantial overestimation in target populations used for planning.
Conclusions:
- Periodic household-based micro-planning, enhanced by technology for validation, is crucial for addressing immunization planning gaps.
- This approach is effective in developing countries like Nigeria facing challenges with overestimated denominators.
- Implementing robust micro-planning can lead to more accurate immunization service delivery and evaluation.
Background:
The OPV 3 coverage for Kaduna State, 12-23 months old children was 34.4%. The low OPV 3 coverage, due mainly to weak demand for routine antigens and the need to rapidly boost population immunity against the disabling Wild Polio Virus (WPV), led the Global Polio Eradication Initiatives (GPEI) to increase supplemental OPV campaigns in Kaduna State, despite the huge cost and great burden on personnel. The OPV campaigns, especially in high risk (low vaccine uptake, <80% OPV 3 coverage and high vaccines refusal rate) states of northern Nigeria with poliovirus transmission has resulted in overestimated denominators or target population, as the highest ever vaccinated is used to set OPV campaign targets.
Methods:
We utilized a cross-sectional study that assessed the impacts and possible solutions to the challenges of overestimated denominators in immunization services planning, delivery and performance evaluation in Kaduna State, Nigeria. We used both descriptive and quantitative approaches. We enumerated households and obtained the target populations for routine immunization (<1 year), polio campaign (<5 years) and acute flaccid paralysis surveillance (<15 years).
Results:
We found a significant difference in mean scores between the micro-planning and supplemental vaccination data on a number of <5 years (M = 102967, SD = 62405, micro-planning compared to M = 157716, SD = 72212, supplemental vaccination, p < 0.05). We also found a significant difference in mean scores between the micro-planning and projected census data on a number of <1 year (M = 26128, SD = 16828, micro-planning compared to M = 14154, SD = 4894, census, p < 0.05).
Conclusion:
Periodic household-based micro-planning, aided with the use of technology for validation remains a useful tool in addressing gaps in immunization planning, delivery and performance evaluation in developing countries, such as Nigeria with overestimated denominators.
Related Concept Videos
Sampling Plans
Random sampling is a method where each member of the population has an equal chance of being selected for the sample. It involves selecting individuals randomly, often using random number generators or lottery-type methods. For example, when analyzing the properties of a...
What is the Immune System?
Planning Nursing Care I
Planning Nursing Care II
Humoral Immune Responses
Role of Communication in the Nursing Process II: Planning and Implementation

