Zebrafish knock-ins swim into the mainstream.

Sergey V Prykhozhij1, Jason N Berman2,3,4

  • 1Department of Pediatrics, Dalhousie University, IWK Health Centre, Halifax, NS B3K 6R8, Canada.

Summary

Researchers are improving CRISPR/Cas9 gene editing in zebrafish to precisely insert mutations for studying human genetic diseases. This enhances the efficiency and applicability of point mutation knock-in techniques.