Related Experiment Video
Updated: Feb 3, 2026

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY
Published on: June 30, 2016
[Metabolic induced changes of the central nervous system]
W Reith1, U Yilmaz2, R Mühl-Bennighaus2
1Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Straße, 66421, Homburg/Saar, Deutschland. wolfgang.reith@uks.eu.
Clinical Issue:
The diagnosis of metabolic disorders of the central nervous system (CNS) can be very challenging for radiologists because of the nonspecific white matter lesions of the brain, the rarity of these diseases, and the variety of possible differential diagnoses.
Radiological Standard Methods:
Standard for the evaluation of the metabolic disorders is cranial MRI. The MRI spectroscopy can additionally help to reduce the possible differential diagnoses.
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