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Updated: Feb 3, 2026

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis
Published on: September 26, 2016
[Intra-arterial procaine injection in peripheral arterial disease]
Sonographically guided procaine injections into femoral arteries effectively treated chronic pain from peripheral arterial disease. This minimally invasive procedure offered significant, long-lasting pain relief for a patient unresponsive to conventional medication.
Area of Science:
- Vascular Surgery
- Pain Management
- Regenerative Medicine
Background:
- Peripheral arterial disease (PAD) causes chronic pain and limits mobility.
- WHO Step III medication is often insufficient for severe PAD pain.
- This case explores an alternative treatment for intractable PAD pain.
Observation:
- A 61-year-old woman with severe PAD pain, unable to walk over 100m, was treated.
- She received sonographically guided procaine injections into bilateral femoral arteries.
- Pain relief was immediate and sustained for 4 weeks post-initial injection.
Findings:
- A repeat injection 4 weeks later provided sustained pain relief for 6 months.
- The treatment demonstrated significant efficacy in managing chronic limb pain.
- Ultrasound guidance ensured precise delivery of the anesthetic agent.
Implications:
- Sonographically guided procaine injections represent a promising therapeutic option for PAD.
- This technique may offer an alternative to more invasive procedures or systemic medication.
- Further research into this minimally invasive approach for vascular pain is warranted.
Related Concept Videos
Peripheral Artery Disease I: Introduction
Peripheral Artery Disease IV: Nursing Management
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Coronary Artery Disease I: Introduction

