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Assay Development for High Content Quantification of Sod1 Mutant Protein Aggregate Formation in Living Cells
Published on: October 4, 2017
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Recent development of portable imaging platforms for cell-based assays
Ke Yang1, Jiandong Wu2, Susy Santos3
1Institute of Applied Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, PR China; Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada.
Biosensors & Bioelectronics
|October 28, 2018
Summary
Portable imaging systems enhance cell-based assays, making them accessible beyond specialized labs. This review covers miniaturized microscopes, lens-free devices, and smartphone microscopes for broader research and clinical use.
Area of Science:
- Biomedical Engineering
- Cell Biology
- Medical Diagnostics
Background:
- Cell-based assays are crucial for life science research and medicine.
- Traditional lab-based assays require specialized facilities, limiting accessibility.
- Portable imaging platforms offer a solution for on-site and wider research use.
Purpose of the Study:
- To review recent advancements in portable cell imaging technologies.
- To discuss the applications of these technologies in cell-based assays.
- To explore future directions in portable cell imaging.
Main Methods:
- Review of miniaturized microscopes.
- Review of lens-free imaging devices.
- Review of smartphone-based microscopes.
Main Results:
- Portable imaging systems are emerging as viable alternatives to traditional lab setups.
- Miniaturized microscopes, lens-free devices, and smartphone microscopes offer diverse capabilities for cell analysis.
- These technologies show promise for expanding the reach of cell-based assays.
Conclusions:
- Portable cell imaging platforms significantly improve assay accessibility for researchers and clinicians.
- Further development is needed to address challenges and unlock the full potential of this field.
- Opportunities exist for innovation in miniaturized and on-site cell analysis.
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