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Related Concept Videos

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RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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CRISPR/Cas9 Genome Editing01:28

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Related Experiment Video

Updated: Feb 3, 2026

Author Spotlight: Advancing Gene Editing in Bamboo Leaves for Sustainable Plastic Alternatives
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[Gene editing technology and its research progress in China].

Yi Ou Chen1,2,3, Ying Bao1, Hua Zheng Ma1

  • 1School of Life Science, Peking University, Beijing 100871, China.

Yi Chuan = Hereditas
|October 30, 2018
PubMed
Summary

Gene editing technologies, including CRISPR/Cas9, enable precise genome modification. This review highlights advancements in gene editing, focusing on applications and new technologies developed in China.

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Area of Science:

  • Molecular Biology
  • Genetics
  • Biotechnology

Background:

  • Gene editing allows precise modification of genome sequences and gene expression.
  • Early gene editing tools include homing endonucleases, zinc finger endonucleases, and transcription activator-like effectors.
  • The CRISPR/Cas9 system is a recent, powerful, and versatile tool for gene editing.

Purpose of the Study:

  • To review recent developments and applications of gene editing technology.
  • To focus on gene editing progress in China.
  • To emphasize mechanistic studies, new technology development, and applications in various fields.

Main Methods:

  • Literature review of gene editing technologies.
  • Focus on CRISPR/Cas9 system advancements.
  • Analysis of applications in animals, plants, and therapeutics.

Main Results:

  • CRISPR/Cas9 has emerged as a versatile gene editing tool.
  • Significant progress in gene editing technologies and applications has been observed, particularly in China.
  • Mechanistic studies and development of novel gene editing technologies are ongoing.

Conclusions:

  • Gene editing technology, especially CRISPR/Cas9, offers broad applications.
  • Continued research is advancing gene editing for agriculture, medicine, and basic science.
  • China is making notable contributions to the field of gene editing.