Related Experiment Video

Updated: Feb 3, 2026

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

17.6K

First Pediatric Case of Infective Endocarditis Caused by Serratia Liquefaciens

Taichi Momose1, Satoshi Masutani1, Ayumi Oshima1

  • 1Department of Pediatrics and Pediatric Cardiology, Saitama Medical Center, Saitama Medical University.

International Heart Journal
|October 30, 2018
PubMed

Insights

Serratia liquefaciens infective endocarditis (IE) is rare in children. This case highlights the first neonatal IE caused by this bacteria, emphasizing broad-spectrum antibiotic use in critical pediatric heart patients.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Neonatal Care

Background:

  • Infective endocarditis (IE) is a serious infection affecting heart valves.
  • Serratia liquefaciens is an uncommon cause of IE, with limited pediatric case reports.
  • Neonates undergoing cardiac surgery are at high risk for healthcare-associated infections.

Observation:

  • A neonatal patient developed IE caused by Serratia liquefaciens post-palliative heart surgery.
  • Mitral valve vegetation was identified as a complication.
  • The infection occurred within days of the surgical procedure.

Findings:

  • This represents the first reported pediatric (neonatal) case of IE due to Serratia liquefaciens.
  • The clinical presentation highlights a potential complication following cardiac surgery in neonates.
  • Serratia liquefaciens can cause severe IE in vulnerable infant populations.

Implications:

  • Early and broad-spectrum antibiotic coverage targeting both gram-positive and gram-negative organisms is crucial in suspected IE cases in neonates.
  • This case expands the understanding of pathogens causing IE in pediatric cardiac surgery patients.
  • Further surveillance and research are needed to understand the epidemiology and optimal management of Serratia liquefaciens IE in neonates.

Keywords:
AntibioticsChromosomal abnormalitiesCongenital heart defectEchocardiographyInfantVegetation

More Related Videos

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip06:11

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Published on: March 29, 2024

2.4K
Guidelines for Elective Pediatric Fiberoptic Intubation11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

18.5K

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
513
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
500
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
258
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
388
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
262
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
304