Related Experiment Video
Updated: Feb 3, 2026
10:36
Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
20.8K
A next generation probiotic, Akkermansia muciniphila
Qixiao Zhai1,2,3, Saisai Feng1,2, Narbad Arjan3,4
1State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Critical Reviews in Food Science and Nutrition
|October 31, 2018
Summary
Akkermansia muciniphila, a gut bacterium, utilizes mucin for energy. Its abundance impacts metabolic and immune health, with disturbances linked to various diseases, highlighting its crucial role in host well-being.
Area of Science:
- Microbiology
- Gastroenterology
- Immunology
Background:
- Akkermansia muciniphila is a symbiotic bacterium residing in the intestinal mucus layer.
- It utilizes mucin as its primary source of carbon, nitrogen, and energy.
- This bacterium is abundant in the gut tracts of both humans and animals.
Purpose of the Study:
- To review the biological characteristics of Akkermansia muciniphila.
- To identify factors influencing its intestinal colonization.
- To discuss its role in host health and disease, particularly metabolic and autoimmune conditions.
Main Methods:
- Literature review of existing studies on Akkermansia muciniphila.
- Analysis of research on its biological properties and colonization factors.
- Synthesis of data regarding its association with various diseases.
Main Results:
- Akkermansia muciniphila possesses unique metabolic capabilities, utilizing mucin effectively.
- Its colonization is influenced by various host and environmental factors.
- Disturbances in Akkermansia muciniphila abundance are linked to metabolic syndromes and autoimmune diseases.
Conclusions:
- Akkermansia muciniphila plays a significant role in maintaining gut health and regulating host metabolism and immunity.
- Understanding its biology and colonization is key to exploring its therapeutic potential.
- Further research is warranted to fully elucidate its impact on health and disease.
Related Concept Videos
01:19DC Generator
2.1K
An alternator converts mechanical energy into electrical energy that varies sinusoidally, resulting in AC current. Meanwhile, a DC generator converts mechanical energy into electrical energy, which are DC pulses with the same polarity. The construction of a DC generator is similar to that of an alternator, except that the pair of slip rings is replaced by a single split ring, also called a commutator. The commutator functions like a periodic rotary switch; it changes the contacts with the...
2.1K
03:00Next-generation Sequencing
98.5K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
98.5K
01:22Generation Time
1.5K
Bacterial generation time, the period required for a bacterial population to double during its exponential growth phase, serves as a critical measure of microbial growth dynamics under optimal conditions. This parameter varies significantly across bacterial species and can be influenced by factors such as temperature, pH, and the availability of nutrients. For example, Escherichia coli can achieve a generation time of approximately 20 minutes, while Mycobacterium tuberculosis exhibits a much...
1.5K
01:25Electric Generator: Alternator
3.4K
Electric generators induce an emf by rotating a coil in a magnetic field. A simple alternator is an AC generator that creates electrical energy that varies sinusoidally with time. A simple alternator consists of a conducting loop that is placed inside a uniform magnetic field. The loop is connected to split rings connected to the external circuit with the help of brushes.
The magnetic flux passing through the coil varies sinusoidally as the loop rotates inside the magnetic field. This...
The magnetic flux passing through the coil varies sinusoidally as the loop rotates inside the magnetic field. This...
3.4K
01:21Generation of Three-Phase Voltage
802
A three-phase AC generator has a rotor with a rotating magnet placed within the stator mounted with the stationary three-phase winding to generate three-phase voltages via mutual induction. These windings are evenly distributed around the inner circumference of the stator and are arranged 120 electrical degrees apart. Three-phase stator windings consist of three separate coils or groups of coils, known as phases, each connected in Y (star) configuration or Delta configuration.
As the rotor...
As the rotor...
802
01:21Generator Voltage Control
660
Generator voltage control is crucial for maintaining the stable operation of synchronous generators and wind turbines. In older models, a DC generator driven by the rotor delivers DC power to the rotor's field winding, and the power is transferred through slip rings and brushes. In the latest models, static or brushless exciters are used. Static exciters rectify AC power from the generator terminals and then transfer the DC power directly to the rotor. Brushless exciters, on the other hand, use...
660