Related Experiment Video
Updated: Feb 3, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Percutaneous Management of Left Atrial Appendage Perforation: Keep Calm and Think Fast
Giovanni Lorenzoni1, Pierluigi Merella, Paolo Pischedda
1Ospedale San Francesco, Unità Operativa Complessa di Cardiologia, via Mannironi 1, Nuoro, Italy. giovannilorenzoni@alice.it.
Insights
Left atrial appendage perforation during closure procedures can occur. This case highlights successful management of cardiac tamponade via device removal and pericardial drainage, avoiding surgery.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Percutaneous left atrial appendage (LAA) closure is an alternative stroke prevention strategy for patients with atrial fibrillation.
- Complications such as LAA perforation can occur during the diagnostic or closure phases of the procedure.
Observation:
- An 83-year-old woman with permanent atrial fibrillation and high risk for thromboembolism and bleeding underwent elective percutaneous LAA closure.
- During the procedure, the patient became hypotensive, and imaging revealed heart perforation with contrast leakage into the pericardial space, confirming cardiac tamponade.
Findings:
- The cardiac tamponade was successfully managed by immediate release of the closure device and pericardial fluid evacuation.
- This intervention effectively stabilized the patient and averted the need for emergent surgical intervention.
Implications:
- This case underscores the importance of prompt recognition and management of LAA perforation during percutaneous LAA closure.
- Non-surgical management, including device removal and pericardial drainage, can be effective in treating cardiac tamponade resulting from LAA perforation.
- This approach offers a potentially life-saving alternative to surgery in select cases of procedural complications.
Abstract:
Left atrial appendage (LAA) perforation is a possible complication not only after release of the closure device, but also during the diagnostic phase due to sheath positioning in the LAA. We present an 83-year-old woman with permanent atrial fibrillation and high thromboembolic and bleeding risk who was admitted for elective percutaneous LAA closure. During angiographic study, she suddenly became hypotensive. Heart perforation with leakage of contrast in the pericardial space was evident and imaging confirmed cardiac tamponade. Rapid release of the closure device and pericardial evacuation allowed the operators to successfully manage the cardiac tamponade and avoid a surgical option.
Related Concept Videos
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Surface Appendages of Archaea
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
Fast Fourier Transform
The computational efficiency of the FFT becomes...
Fast Decoupled and DC Powerflow
Gene Evolution - Fast or Slow?
In contrast, regions which code...

