Related Experiment Video
Updated: Feb 3, 2026

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
Published on: October 20, 2023
Novel Cerebral Protection Technique During Right Transcarotid TAVR in Bicuspid Aortic Stenosis and Porcelain Aorta
Brett Hiendlmayr1, Kerry E McGuire, Lauren E Curtis
1Hartford Hospital, University of Connecticut, 85 Seymour Street, Hartford, CT 06106 USA. bjh02002@ gmail.com.
Insights
Cerebral embolic protection can reduce stroke during transcatheter aortic valve replacement (TAVR). This case demonstrates successful protection during a transcarotid TAVR, an approach where standard devices are not usable.
Area of Science:
- Cardiovascular Medicine
- Neurology
- Medical Devices
Background:
- Transcatheter aortic valve replacement (TAVR) is a common procedure for aortic stenosis.
- Periprocedural stroke is a significant complication of TAVR, increasing patient morbidity and mortality.
- Cerebral embolic protection devices (CEPDs) like the Sentinel device have shown efficacy in reducing stroke during transfemoral TAVR.
Abstract:
Periprocedural stroke related to transcatheter aortic valve replacement (TAVR) is associated with increased morbidity and mortality. Cerebral embolic protection using the Sentinel device (Claret Medical) has demonstrated reduced rates of stroke during TAVR. However, alternative access such as a transcarotid approach precludes the use of the Sentinel device. We report a case using cerebral embolic protection during a right transcarotid TAVR.
Related Concept Videos
The Aorta
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...
The Arch of Aorta
Encircling the heart, the coronary arteries form a ring-like structure before...
Thoracic Aorta
Abdominal Aorta
The celiac trunk, a singular artery, divides into the left gastric artery, which...
Mitral Stenosis I: Introduction
Anatomy of the Heart

