Related Experiment Video
Updated: Feb 3, 2026
05:41
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
1.1K
Well-Differentiated Liposarcoma Localized to the Thyroid Gland
Amruth R Palla1, Craig Allen Bollig2, Jeffrey Brian Jorgensen2
1Division of Hematology and Oncology, Department of Internal Medicine, Ellis Fischel Cancer Center, University of Missouri Columbia, Columbia, Missouri, USA.
European Thyroid Journal
|October 31, 2018
Summary
Thyroid liposarcoma is rare, lacking a standard treatment. This case highlights successful surgical management and surveillance for well-differentiated liposarcoma, with no recurrence at nine months.
Area of Science:
- Endocrinology
- Oncology
- Surgical Pathology
Background:
- Thyroid liposarcoma is an exceptionally rare malignancy.
- Limited case data hinders establishing definitive treatment protocols.
Purpose of the Study:
- To report a case of well-differentiated thyroid liposarcoma.
- To review existing literature on thyroid liposarcoma.
- To discuss potential management strategies for this rare tumor.
Main Methods:
- Surgical resection of the thyroid mass.
- Post-operative surveillance including clinical examination and Magnetic Resonance Imaging (MRI).
- Comprehensive literature review of previously reported thyroid liposarcoma cases.
Main Results:
- A 49-year-old male patient with a well-differentiated liposarcoma underwent successful surgical treatment.
- At 9-month follow-up, the patient showed no clinical or radiological evidence of recurrence.
- The patient maintained good speech and swallowing functions post-surgery.
Conclusions:
- Surgical excision followed by close surveillance may be a viable approach for well-differentiated thyroid liposarcoma.
- Further case accumulation and analysis are crucial for developing optimal treatment guidelines.
- This case contributes to the limited understanding of thyroid liposarcoma management and outcomes.
Related Concept Videos
01:23The Thyroid Gland
7.7K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.7K
01:24Local Anesthetics: Differential Sensitivity of Nerve Fibers
1.4K
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
1.4K
01:18Functions of Thyroid Hormones
5.6K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
5.6K
01:29Exocrine Glands: Unicellular and Multicellular Glands
32.6K
Exocrine glands are classified as unicellular and multicellular. The unicellular glands are scattered single cells, such as goblet cells, found in the mucous membranes of the small and large intestines. On the other hand, multicellular exocrine glands develop as secretory sheets, like the internal lining of the abdomen or chest. Such secretory sheets release their secretions directly into the lumen of these organs. In addition, some multicellular glands have deep-seated secretory units to...
32.6K
01:20Synthesis and Regulation of Thyroid Hormones
7.8K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
7.8K
01:17The Pituitary Gland
10.8K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
10.8K