Spontaneous Coronary Artery Dissection: an Overview.
1Division of Cardiology, Kaiser Northern California, 2238 Geary Boulevard, 8th Floor, San Francisco, CA, USA. sahar.naderi@kp.org.
Current Atherosclerosis Reports
|October 31, 2018
Summary
Spontaneous coronary artery dissection (SCAD) is a heart condition affecting women, causing heart attacks without typical risk factors. More research is crucial for better understanding and patient care.
Area of Science:
- Cardiology
- Vascular Medicine
Background:
- Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic cause of acute myocardial infarction (AMI).
- SCAD predominantly affects pre- or perimenopausal women lacking traditional cardiovascular disease risk factors.
- It is distinct from inflammatory or traumatic arterial conditions.
Purpose of the Study:
- To review the epidemiology, diagnosis, and management of SCAD.
- To highlight the need for further research into SCAD patient care.
- To discuss recent insights from consensus statements and pregnancy-associated SCAD.
Main Methods:
- Literature review focusing on SCAD epidemiology, diagnosis, and management.
- Analysis of recent American Heart Association consensus statements.
- Examination of data on pregnancy-associated SCAD.
Main Results:
- SCAD is an under-recognized cause of AMI, particularly in women.
- Recent advancements include a consensus statement and better characterization of pregnancy-associated SCAD.
- Increased identification of SCAD by healthcare professionals and first responders has occurred.
Conclusions:
- Despite increased awareness, significant knowledge gaps remain regarding SCAD.
- Further research with larger patient cohorts is essential for improved understanding and treatment.
- SCAD patient care requires continued investigation and dedicated research efforts.
Related Concept Videos
01:30Coronary Artery Disease I: Introduction
1.1K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.1K
01:26Coronary Artery Disease II: Pathophysiology
451
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
451
02:21Spontaneity
30.0K
A spontaneous process is one that occurs naturally under certain conditions. A nonspontaneous process, on the other hand, will not take place unless it is “driven” by the continual input of energy from an external source. Processes have a natural tendency to occur in one direction under a given set of conditions. Water will naturally flow downhill (spontaneous process), but uphill flow (nonspontaneous process) requires outside intervention such as the use of a pump. Iron exposed to...
30.0K
01:27Coronary Artery Disease V: Interprofessional Care
269
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
269
01:11Overview of Systemic Arteries
1.9K
The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
1.9K
01:30Coronary Artery Disease III: Clinical Manifestations
373
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
373