Related Experiment Videos
Malignant clear-cell hidradenoma
Insights
This case report details a rare malignant clear-cell hidradenoma on the hand. Early aggressive surgery is advised due to treatment resistance, with lung and myocardial metastases noted.
Area of Science:
- Dermatopathology
- Surgical Oncology
Background:
- Malignant clear-cell hidradenoma is a rare skin neoplasm.
- Complete reports with follow-up and necropsy are exceptionally scarce in medical literature.
Observation:
- A case of malignant clear-cell hidradenoma on the dorsum of the hand is presented.
- This tumor exhibited significant invasiveness.
- The case is unique for documenting both lung and myocardial metastases.
Findings:
- The patient underwent wide surgical excision and radical node dissection.
- Recurrence necessitated arm amputation.
- Radiotherapy and chemotherapy proved ineffective in this case.
Implications:
- Early, aggressive surgical intervention, including regional lymph node dissection, is recommended for malignant clear-cell hidradenoma.
- Close patient follow-up is crucial post-surgery.
- This case highlights the aggressive potential and metastatic capabilities of this rare tumor.
Abstract:
In this paper the authors present a case of malignant clear-cell hidradenoma developed on the dorsum of the hand. This is only the eleventh complete report in the literature, including follow-up, and only the third to include necropsy. It is the first to find both lung and myocardial metastases. The tumor was very invasive and was treated first by wide surgical excision and radical node dissection, and when the tumor recurred, amputation of the arm was done. The world literature was carefully reviewed and compared with this case. Owing to the already known failure of radiotherapy, and since chemotherapy was not successful in our patient, the authors advise early aggressive surgery, including block dissection of the regional nodes, and thereafter a careful follow-up.