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Updated: Feb 3, 2026

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[Microscopic Colitis].

Lisa Högger1, Stephan Vavricka2

  • 11 Klinik für Allgemein-, Viszeral- und Gefässchirurgie, Kantonsspital Baden.

Praxis
|November 1, 2018
PubMed
Summary

Microscopic colitis (MC) causes chronic watery diarrhea, often in older women. Early diagnosis and treatment are crucial for improving quality of life in patients with this increasingly recognized condition.

Keywords:
AutoimmunerkrankungColite microscopiqueLebensqualitätMicroscopic colitisMikroskopische Kolitisautoimmune diseasecolite collagènecolite lymphocytairecollagenous colitiskollagene Kolitislymphocytic colitislymphozytäre Kolitismaladie auto-immunequality of lifequalité de vie

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Area of Science:

  • Gastroenterology
  • Histopathology

Background:

  • Microscopic colitis (MC) is an underdiagnosed cause of chronic, non-bloody watery diarrhea.
  • It predominantly affects elderly females and is increasingly diagnosed.
  • The etiology and pathophysiology are not fully understood, but associations with autoimmune diseases and potential genetic predispositions exist.

Purpose of the Study:

  • To raise awareness for microscopic colitis.
  • To highlight the importance of diagnosis and therapy for this condition.

Main Methods:

  • Diagnosis relies on histological examination of colonic biopsies.
  • Key subtypes include lymphocytic colitis (LC) and collagenous colitis (CC).

Main Results:

  • Microscopic colitis leads to chronic, recurrent symptoms.
  • Despite a generally benign long-term course, symptoms significantly impair health-related quality of life.

Conclusions:

  • Accurate diagnosis and timely management of microscopic colitis are essential.
  • Increased awareness is needed to address this condition and its impact on patients.