Related Experiment Video
Updated: Feb 3, 2026

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa
Published on: February 17, 2014
In silico analysis of transferable QepA variants and related chromosomal efflux pumps
1Joaquim Ruiz, P.O.Box 16, 08214-Badia del Valles, Spain. joruiz.trabajo@gmail.com.
Objective:
The present study aimed to detect the presence of undescribed QepA variants in GenBank records.
Methods:
The DNA and amino acid sequences of QepA1 were compared with what is present in GenBank. Only annealings with a >80% identity were considered. No synthetic or partial sequences were included in the analyses.
Results:
The results showed the presence of 10 different QepA variants, 6 of them which were previously non-designated as specific allelic variants. In addition, high identity levels with chromosomal MSF efflux pumps belonging to microorganisms of the Pseudorhodoferax genus and other Comamonadaceae were detected.
Conclusions:
The presence of undescribed QepA variants in GenBank is reported and the presence of related sequences among members of Burkholderiales order is described.
More Related Videos
07:17Improving the Accuracy of Flow Cytometric Assessment of Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells Through the Inhibition of Efflux Pumps
Published on: July 30, 2019
08:18High-throughput Nitrobenzoxadiazole-labeled Cholesterol Efflux Assay
Published on: January 7, 2019
Related Concept Videos
Histone Variants at the Centromere
Chromosome Structure
The centromere is a DNA sequence that links sister chromatids. This is also where kinetochores, protein complexes to which spindle microtubules attach, are constructed after the chromosome is replicated. The kinetochores allow the spindle microtubules to move the chromosomes within the cell during cell division.
Telomeres consist of non-coding repetitive nucleotide...
Polytene Chromosomes
Lampbrush Chromosomes
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops...
Chromosome Replication
Chromosomal Theory of Inheritance