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Published on: July 30, 2007
Construction of highly sterically hindered 1,1-disilylated terminal alkenes
Xueyan Zhang1, Xin Ji, Xingze Xie
1State Key Laboratory of Organic-Inorganic Composites, College of Chemical Engineering, Beijing University of Chemical Technology, Beijing, 100029, China. stding@mail.buct.edu.cn.
Abstract:
One direct and efficient procedure for the synthesis of 1,1-disilylated terminal alkenes is demonstrated in this paper. To overcome and rationally utilize the steric hindrance of silyl units, the cationic ruthenium catalyst [CpRu(MeCN)3]+ was found to be effective for Markovnikov hydrosilylation of 1-silyl terminal alkynes with high yields and excellent regioselectivity. Dissimilarities between alkyl and alkoxy silyl units lead to versatile product derivatizations toward a variety of useful building blocks.
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