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Inducement and Evaluation of a Murine Model of Experimental Myopia
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Myopia and orthokeratology for myopia control
1School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.
Clinical & Experimental Optometry
|November 1, 2018
Summary
Childhood myopia is a growing global health issue. Orthokeratology and atropine therapy show promise for myopia control, with combined treatments potentially maximizing effectiveness.
Area of Science:
- Ophthalmology
- Public Health
- Pediatrics
Background:
- Childhood myopia prevalence is rising globally, posing a significant public health concern.
- Higher myopia rates are observed in East Asian children, potentially linked to increased near-work and reduced outdoor time.
- Mechanisms of myopia onset and progression remain incompletely understood.
Purpose of the Study:
- To review current research on myopia prevention and control strategies in children.
- To discuss the efficacy and unanswered questions regarding orthokeratology and atropine therapy.
- To explore the potential of combined myopia control interventions.
Main Methods:
- Literature review of studies on myopia prevalence, risk factors, and treatment efficacy.
- Analysis of findings on orthokeratology and atropine therapy for slowing axial elongation.
- Discussion of clinical considerations and future research directions.
Main Results:
- Orthokeratology is effective in slowing axial elongation and is widely used, particularly in East Asia.
- Atropine therapy also demonstrates efficacy in slowing myopia progression through a potentially different mechanism.
- Combined orthokeratology and atropine therapy may offer enhanced myopia control.
Conclusions:
- Orthokeratology and atropine are key interventions for childhood myopia control.
- Further research is needed to optimize treatment duration, dosage, and patient selection for these therapies.
- Combined therapies hold significant potential for maximizing myopia control effectiveness in children.
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