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CT-707 Overcomes Resistance of Crizotinib through Activating PDPK1- AKT1 Pathway by Targeting FAK

Caixia Liang1, Ningning Zhang1, Qiaoyun Tan1

  • 1Department of Medical Oncology, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, National Cancer Center/National Clinical Research Center for Cancer/ Cancer Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100021, China.

Current Cancer Drug Targets
|November 2, 2018
PubMed
Abstract

Keywords:
Anaplastic lymphoma kinaseCT-707crizotinib resistancenon-small cell lung cancertherapeutic agentxenograft model.

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