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Nanostructured Systems in Advanced Drug Targeting for the Cancer Treatment: Recent Patents
Maricruz Anaya-Ruiz1, Cindy Bandala2, Gerardo Landeta3
1Cell Biology Laboratory, Biomedical Research Center of the East, Mexican Institute of Social Security, Metepec, Puebla CP 74360, Mexico.
Background:
Cancer is one of the leading causes of death in the world and it is necessary to develop new strategies for its treatment because most therapies have limited access to many types of tumors, as well as low therapeutic efficacy and high toxicity.
Objective:
The present research aims to identify recent patents of drug delivery nanostructured systems that may have application in improving cancer treatment.
Methods:
Recent patents regarding the drug delivery nanostructured systems for cancer treatment were obtained from the patent databases of the six main patent offices of the world: United States Patent and Trademark Office, European Patent Office, World Intellectual Property Organization, Japan Patent Office, State Intellectual Property Office of China and Korean Intellectual Property Office.
Results:
A total of 1710 patent documents from 1998 to 2017 including "drug delivery nanostructured systems for cancer treatment" were retrieved. The top five countries in patent share were USA, China, South Korea, Canada and Germany. The universities and enterprises of USA had the highest amount of patents followed by institutions from China.
Conclusion:
There is a strong tendency for the development of new nanostructured systems for the release of drugs; particularly, in recent years, the development of nanoparticles has focused on nanodiscs, gold nanoparticles and immunoliposomes.
Insights
Researchers analyzed patents for nanostructured drug delivery systems to improve cancer treatment. Recent developments show a focus on nanoparticles like nanodiscs, gold nanoparticles, and immunoliposomes for enhanced cancer therapy.
Area of Science:
- Biotechnology
- Nanotechnology
- Oncology
Background:
- Cancer remains a leading global cause of death.
- Current cancer therapies face challenges with tumor accessibility, efficacy, and toxicity.
- Novel treatment strategies are crucial for effective cancer management.
Purpose of the Study:
- To identify and analyze recent patents for nanostructured drug delivery systems in cancer treatment.
- To understand the landscape of innovation in nanomedicine for oncology.
Main Methods:
- A comprehensive patent search was conducted across six major global patent offices.
- Keywords used included 'drug delivery nanostructured systems for cancer treatment'.
- Patent documents from 1998 to 2017 were analyzed.
Main Results:
- 1710 patent documents were retrieved, indicating significant research activity.
- The USA, China, and South Korea lead in patent filings for these systems.
- US and Chinese institutions show the highest patent contributions.
Conclusions:
- There is a clear trend towards developing advanced nanostructured systems for drug delivery.
- Recent innovations concentrate on specific nanoparticle types such as nanodiscs, gold nanoparticles, and immunoliposomes.
- These nanomedicine advancements hold promise for improving cancer treatment outcomes.
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