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The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
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Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
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[PET/CT Simulation for Radiation Therapy Planning].

Kohei Hanaoka1,2, Masahiko Okumura3, Hajime Monzen2

  • 1Institute of Advanced Clinical Medicine, Division of Positron Emission Tomography, Kindai University.

Igaku Butsuri : Nihon Igaku Butsuri Gakkai Kikanshi = Japanese Journal of Medical Physics : an Official Journal of Japan Society of Medical Physics
|November 2, 2018
PubMed
Summary
This summary is machine-generated.

18F-FDG PET/CT enhances radiation therapy planning by providing biological insights for tumor delineation. However, challenges remain in standardizing image thresholds and addressing false positives, impacting clinical target accuracy.

Keywords:
BTVFDGPETPET/CT

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Area of Science:

  • Nuclear Medicine
  • Radiotherapy Oncology
  • Medical Imaging

Background:

  • 18F-FDG PET/CT is crucial for radiation therapy planning, offering prognostic and predictive data.
  • It provides biological information for defining gross tumor volume (GTV) and nodal disease.
  • Studies confirm PET's significant impact on radiation therapy planning for many patients.

Purpose of the Study:

  • To evaluate the role and limitations of 18F-FDG PET/CT in radiation therapy planning.
  • To highlight the prognostic and predictive value of PET/CT parameters.
  • To identify challenges in integrating PET/CT data into clinical target delineation.

Main Methods:

  • Review of existing studies on 18F-FDG PET/CT in radiation therapy planning.
  • Analysis of PET/CT parameters like Standard Uptake Value (SUV) and Metabolic Tumor Volume (MTV).
  • Assessment of methods for defining Gross Tumor Volume (GTV) using PET/CT imaging.

Main Results:

  • 18F-FDG PET/CT significantly impacts radiation therapy planning in a substantial patient proportion.
  • PET/CT parameters like SUV and MTV offer crucial prognostic and predictive information.
  • Challenges include the lack of established optimal thresholds for GTV delineation and potential false positives from benign conditions.

Conclusions:

  • 18F-FDG PET/CT is valuable for radiation therapy planning, improving tumor definition.
  • Standardization of image analysis, particularly threshold selection, is needed for consistent GTV delineation.
  • Addressing the non-cancer-specific nature of FDG and interdisciplinary collaboration are essential for optimal use.