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[Targeted Radioisotope Therapy-Current Status and Future Perspectives]
1Dept. of Molecular Imaging and Theranostics, National Institute of Radiological Sciences(NIRS), National Institutes for Quantum and Radiological Science and Technology(QST).
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|November 2, 2018
Summary
Precision medicine is advancing with targeted radioisotope therapy (TRT), combining diagnosis and treatment using molecular probes. This approach utilizes different radioactive isotopes for imaging and therapeutic applications.
Area of Science:
- Nuclear Medicine
- Oncology
- Radiochemistry
Background:
- Precision medicine integrates diagnostics and therapeutics.
- Targeted Radioisotope Therapy (TRT) is an emerging modality in nuclear medicine.
- TRT utilizes molecular-targeted probes for both imaging and treatment.
Purpose of the Study:
- To provide a summary of targeted radioisotope therapy.
- To discuss future perspectives of TRT.
- To highlight the use of beta and alpha emitters in TRT.
Main Methods:
- Review of current literature on TRT.
- Analysis of molecular-targeted probes.
- Discussion of radioisotopes (beta and alpha emitters).
Main Results:
- TRT offers a dual capability for diagnosis and therapy.
- Various molecular probes are being developed for TRT.
- Beta and alpha emitters show promise for targeted treatment.
Conclusions:
- Targeted Radioisotope Therapy represents a significant advancement in precision medicine.
- Further research into novel probes and radioisotopes will expand TRT applications.
- TRT holds potential for improved patient outcomes in various diseases.
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