Related Experiment Video
Updated: Feb 3, 2026

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
Published on: March 7, 2019
The Relationships Between Physical Performance, Activity Levels, and Falls in Older Men
Eric S Orwoll1, Nora F Fino2, Thomas M Gill3
1Department of Medicine, Bone and Mineral Unit, Oregon Health & Science University, Portland.
Fall risk in older men is linked to both physical activity and performance. While low levels of both increase falls, high activity also shows a peak in fall risk, suggesting complex interactions.
Area of Science:
- Gerontology
- Epidemiology
- Biomedical Science
Background:
- Physical performance and activity are known risk factors for falls in older adults.
- The combined impact of physical activity and performance on fall risk remains unclear.
- This study investigates the joint association of these factors with incident falls in elderly men.
Purpose of the Study:
- To examine how physical activity and physical performance are jointly associated with incident falls in older men.
- To identify specific patterns of activity and performance that confer the highest fall risk.
- To inform targeted fall prevention strategies for older men.
Main Methods:
- A cohort of 2,741 men (mean age 78.8 years) was studied.
- Physical activity was measured using accelerometry.
- Physical performance was assessed via gait speed, dynamic balance, chair stand test, grip strength, and leg power.
- Falls were recorded through tri-annual questionnaires.
Main Results:
- Men with low activity and low physical performance experienced the highest number and rate of falls.
- A significant portion of falls also occurred in men with low activity/high performance and high activity/high performance.
- Interactions between activity, performance (gait speed, narrow walk), and falls were significant (p = .001–.02), with a secondary peak in fall risk observed in highly active men.
Conclusions:
- While low physical activity and performance significantly increase fall risk in older men, substantial fall risk exists across other combinations of activity and performance levels.
- Integrated assessments of physical activity and performance can enhance the identification of older men at risk of falls.
- Individualized fall prevention strategies tailored to specific activity and performance profiles are recommended.
Related Concept Videos
Relationship Formation
Structure-Activity Relationships and Drug Design
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
Free-falling Bodies: Example
The...
Local Anesthetics: Chemistry and Structure-Activity Relationship
Cholinergic Antagonists: Chemistry and Structure-Activity Relationship
Adrenergic Agonists: Chemistry and Structure-Activity Relationship
Aromatic ring substitutions: Substituting the aromatic ring with –OH groups at positions 3 and 4 yields catecholamines (e.g., epinephrine), which have a high affinity for adrenoceptors. Hydrogen bonding between –OH groups and receptors enhances adrenergic activity.
Separation of...

