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The Auditory Ossicles01:11

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Related Experiment Video

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Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI
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Distress tolerance to auditory feedback and functional connectivity with the auditory cortex.

Merideth A Addicott1, Stacey B Daughters2, Timothy J Strauman3

  • 1Department of Psychiatry, University of Arkansas for Medical Science, 4301 W. Markham St., #843, Little Rock, AR 72205, USA.

Psychiatry Research. Neuroimaging
|November 2, 2018
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Summary

Low distress tolerance is linked to brain activity connecting auditory processing and the anterior insula. This neural pathway may mediate avoidance of distressing situations, impacting goal pursuit.

Keywords:
Auditory cortexDistress toleranceEmotion regulationFunctional connectivityInsulafMRI

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Area of Science:

  • Neuroscience
  • Psychology

Background:

  • Distress tolerance, the ability to withstand negative emotions for goals, is crucial.
  • Poor distress tolerance can lead to avoidance, but underlying neural mechanisms are unclear.

Purpose of the Study:

  • Investigate neural mechanisms of distress generation and avoidance.
  • Examine the relationship between brain activity and distress tolerance.

Main Methods:

  • Healthy participants underwent neuroimaging while performing a mental arithmetic task with varying difficulty and feedback.
  • Distress tolerance was measured by persistence in a distressing task phase for financial reward.
  • Functional connectivity analysis focused on the left secondary auditory cortex (planum temporale).

Main Results:

  • Both easy and distress phases activated auditory and fronto-parietal regions.
  • Distress phase showed stronger connectivity between the planum temporale and fronto-parietal regions/anterior insula.
  • Connectivity between the planum temporale and left anterior insula negatively correlated with distress tolerance.

Conclusions:

  • The anterior insula may act as a neural mediator.
  • This mediation links the generation of distress to behavioral avoidance.
  • Findings shed light on the neural basis of distress tolerance and avoidance behaviors.