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Updated: Feb 3, 2026

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
Published on: September 25, 2021
Salivary calculi microbiota: new insights into microbial networks and pathogens reservoir
Roberta De Grandi1, Pasquale Capaccio2, Alessandro Bidossi1
1Laboratory of Clinical Chemistry and Microbiology, IRCCS Orthopedic Institute Galeazzi, via R. Galeazzi 4, 20161 Milan, Italy.
Abstract:
Sialolithiasis represents the most common disorders of salivary glands in middle-aged patients. It has been hypothesized that the retrograde migration of bacteria from the oral cavity to gland ducts may facilitate the formation of stones. Thus, in the present study, a microbiome characterization of salivary calculi was performed to evaluate the abundance and the potential correlations between microorganisms constituting the salivary calculi microbiota. Our data supported the presence of a core microbiota of sialoliths constituted principally by Streptococcus spp., Fusobacterium spp. and Eikenella spp., along with the presence of important pathogens commonly involved in infective sialoadenitis.
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