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Updated: Feb 3, 2026
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Reconstruct Human Retinoblastoma In Vitro
Published on: October 11, 2022
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Retinoblastoma in Asia
Mukesh Jain1, Duangnate Rojanaporn2, Bhavna Chawla3
1Shri Bhagwan Mahavir Vitreoretinal Services, Medical Research Foundation, Sankara Nethralaya, Chennai, 600006, Tamil Nadu, India.
Eye (London, England)
|November 3, 2018
Summary
Retinoblastoma (RB) significantly impacts the Asia-Pacific region, with 43% of global cases concentrated there. Addressing socio-economic disparities is crucial for improving culturally relevant and economically feasible interventions for this childhood cancer.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Global Health
Background:
- The Asia-Pacific region shoulders a substantial global burden of retinoblastoma (RB), a significant childhood eye cancer.
- In 2013, 43% of global RB cases occurred in six Asia-Pacific countries, highlighting regional disparities.
- Technological and socio-economic variations within the region contribute to diverse clinical presentations and survival rates.
Purpose of the Study:
- To underscore the importance of understanding retinoblastoma in the Asia-Pacific region.
- To identify socio-economic challenges and opportunities for intervention development.
- To propose actionable steps for improving RB care and outcomes in developing nations.
Main Methods:
- Analysis of 2013 population estimates to determine the global burden of retinoblastoma.
- Review of existing literature on technological and socio-economic disparities in the region.
- Identification of potential strategies for disease management and intervention.
Main Results:
- India and China account for the highest numbers of retinoblastoma cases in the region.
- Significant disparities in clinical presentation and survival rates exist due to socio-economic factors.
- Challenges in managing retinoblastoma are multifaceted, encompassing technological, social, and economic aspects.
Conclusions:
- Effective interventions for retinoblastoma in the Asia-Pacific must be culturally relevant and economically feasible.
- Key strategies include disease education, universal screening, subsidized treatment, and enhanced healthcare infrastructure.
- Developing specialized centers with tele-ophthalmology services can improve access to care and outcomes for children with retinoblastoma.
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