Prevalence of enteric adenovirus from acute gastroenteritis: a five year study

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Updated: Oct 6, 2026

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay
11:09

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay

Published on: September 11, 2016

R Cevenini, R Mazzaracchio, F Rumpianesi

    European Journal of Epidemiology
    |June 1, 1987
    PubMed

    Insights

    Enteric adenoviruses were endemic in hospitalized pediatric patients with acute gastroenteritis between 1981 and 1985. These viruses showed seasonal variations, impacting public health surveillance strategies.

    Area of Science:

    • Virology
    • Pediatric Infectious Diseases
    • Public Health

    Background:

    • Acute gastroenteritis is a common cause of hospitalization in children.
    • Adenoviruses are significant viral pathogens contributing to pediatric gastroenteritis.

    Purpose of the Study:

    • To determine the prevalence and characteristics of adenoviruses in hospitalized children with acute gastroenteritis.
    • To investigate the seasonality and endemicity of enteric adenoviruses over a five-year period.

    Main Methods:

    • Stool samples from 3932 pediatric patients were analyzed for adenovirus detection.
    • Adenovirus isolates were identified using genus-specific ELISA and cell culture (HEp-2 and 293 cells).

    Main Results:

    • Adenoviruses were detected in 11.6% of children; enteric adenoviruses accounted for 8.3%.
    • Enteric adenoviruses demonstrated endemicity over five consecutive years (1981-1985).
    • A distinct seasonal pattern was observed in adenovirus detection rates.

    Conclusions:

    • Enteric adenoviruses are a persistent cause of acute gastroenteritis in hospitalized children.
    • Understanding adenovirus seasonality is crucial for effective disease control and prevention strategies.
    • Comparative data on rotavirus prevalence were also noted in the study population.

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