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Related Experiment Videos

Experimental vitreous haemorrhage: echographic appearances.

J V Forrester, G R Sutherland, M McDonald

    Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe'S Archive for Clinical and Experimental Ophthalmology
    |October 28, 1977
    PubMed
    Summary

    Ultrasonic examination effectively diagnoses vitreous membranes resulting from haemorrhages. These membranes, composed of blood cells and collagen, show distinct echo patterns and may be treatable with surgery.

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    Area of Science:

    • Ophthalmology
    • Medical Imaging
    • Pathology

    Background:

    • Vitreous haemorrhages can lead to vision impairment.
    • Accurate diagnosis of vitreous opacities and membranes is crucial for effective treatment.
    • Current diagnostic methods may have limitations in visualizing subtle changes.

    Purpose of the Study:

    • To correlate echographic findings (A-scan and B-scan ultrasonography) with gross and histologic appearances of induced vitreous haemorrhages in rabbits.
    • To evaluate the diagnostic capability of combined A- and B-scan ultrasonography for vitreous membranes.
    • To assess the potential surgical amenability of these identified vitreous membranes.

    Main Methods:

    • Vitreous haemorrhages were experimentally induced in a rabbit model.

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  • Echographic examinations using A-scan and B-scan were performed over twenty weeks.
  • Correlations were made between ultrasound findings, gross pathology, and histologic examination.

    • Main Results:

    • Visible vitreous opacities consistently produced distinct echo patterns on ultrasound.
    • As haemorrhages resolved, echo amplitudes decreased progressively.
    • B-scan revealed characteristic patterns of vitreous membranes, histologically confirmed as composed of red blood cells, macrophages, and collagen.

    Conclusions:

    • Combined A- and B-scan ultrasonography is a reliable method for diagnosing haematogenous vitreous membranes.
    • The distinct echographic signatures of these membranes suggest they are readily identifiable.
    • The findings indicate that such vitreous membranes may be candidates for surgical intervention.