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Closing the knowledge gaps on MERS: three and half years since its detection, what have we learnt and what needs to

Mamunur Rahman Malik1, Jaouad Mahjour2

  • 1Coordinator, Health Security & Regulations Cluster, World Health Organization Regional Office for Eastern Mediterranean, Cairo, Egypt.

Eastern Mediterranean Health Journal = La Revue De Sante De La Mediterranee Orientale = Al-Majallah Al-Sihhiyah Li-Sharq Al-Mutawassit
|November 3, 2018
PubMed

Insights

Middle East respiratory syndrome coronavirus (MERS-CoV) remains a global health concern. Ongoing cases and knowledge gaps about its transmission hinder effective response efforts.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012, posing ongoing health risks.
  • Monthly MERS-CoV cases continue to be reported, predominantly from Saudi Arabia and the Arabian Peninsula.
  • Over 85% of detected MERS-CoV cases originate from the Arabian Peninsula.

Discussion:

  • Significant knowledge gaps persist regarding the MERS-CoV source and transmission routes.
  • These uncertainties complicate and hinder a comprehensive global response to the emerging infection.
  • The virus's low transmission levels contrast with its uncertain future impact.

Key Insights:

  • MERS-CoV surveillance and reporting remain critical due to persistent cases.
  • Understanding the viral reservoir and transmission dynamics is essential for control.
  • The geographic concentration of cases highlights regional vulnerability.

Outlook:

  • Continued research is vital to address MERS-CoV knowledge gaps.
  • Enhanced surveillance and international collaboration are necessary for effective management.
  • Addressing the source and transmission routes is key to mitigating future outbreaks.

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