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Oral cancer and tobacco: developments in harm reduction
1Consultant in Oral Medicine and Honorary Professor, Division of Dentistry, Faculty of Biology, Medicine and Health, University of Manchester; University Dental Hospital of Manchester, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M15 6FH.
British Dental Journal
|November 3, 2018
Summary
Oral cancer risk is linked to tobacco, with combustion products posing the highest danger. This review examines evolving tobacco and nicotine product use and their oral cancer risks.
Area of Science:
- Oncology
- Public Health
- Toxicology
Background:
- Oral squamous cell carcinoma (OSCC) is strongly associated with tobacco product use.
- While nicotine is addictive, tobacco combustion yields major carcinogenic substances.
- Cigarette smoking, the highest risk tobacco use, is declining in the UK but prevalent globally.
Purpose of the Study:
- To review changing patterns of tobacco and nicotine consumption.
- To evaluate the current evidence on the oral cancer risk associated with novel nicotine delivery products.
Main Methods:
- Literature review of tobacco and nicotine consumption trends.
- Analysis of epidemiological and toxicological data on oral cancer risk.
Main Results:
- Sweden's reduced smoking rates correlate with snus use.
- New products like heat-not-burn and electronic cigarettes are emerging.
- Tobacco industry actively markets these novel products.
Conclusions:
- The evolving landscape of tobacco and nicotine products necessitates ongoing risk assessment for oral cancer.
- Understanding the carcinogenicity of newer products is crucial for public health strategies.
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