Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glomerular Filtration01:15

Glomerular Filtration

5.4K
The filtration membrane in the renal system is a highly specialized structure essential for filtering blood. It consists of glomerular capillaries and podocytes, forming a selective barrier that permits the passage of water and small solutes while restricting most plasma proteins and blood cells.
Components of the Filtration Membrane
The filtration process involves three key layers: the glomerular endothelial cells, the basement membrane, and the podocyte-formed filtration slits.
5.4K
Glomerular Filtration Rate and its Regulation01:28

Glomerular Filtration Rate and its Regulation

5.4K
The Glomerular Filtration Rate (GFR) is a measure of kidney function, reflecting the volume of filtrate formed per minute in the kidneys. On average, GFR is approximately 125 mL/min in males and 105 mL/min in females. Maintaining a relatively constant GFR is essential for the kidneys to effectively regulate body fluid homeostasis and maintain extracellular stability.
GFR regulation involves two primary intrinsic controls: the myogenic and tubuloglomerular feedback mechanisms.
The myogenic...
5.4K
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration01:28

Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

233
Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
233
Glomerular Filtration: Net Filtration Pressure01:26

Glomerular Filtration: Net Filtration Pressure

8.2K
Glomerular filtration, a key process in the kidneys, is regulated by three main pressures: Glomerular blood hydrostatic pressure (GBHP), Capsular hydrostatic pressure (CHP), and Blood colloid osmotic pressure (BCOP).
GBHP, with an average value of 55 mmHg, promotes filtration by pushing water and solutes through the filtration membrane. This is balanced by two opposing forces: CHP, a "back pressure" exerted against the filtration membrane by fluid already in the capsular space and renal...
8.2K
Renal Drug Excretion: Glomerular Filtration01:02

Renal Drug Excretion: Glomerular Filtration

1.3K
The kidney serves as the primary organ responsible for eliminating drugs and their metabolites from the body. This process, known as renal elimination, starts with glomerular filtration and results in urine formation. Each kidney houses millions of functional units called nephrons, where urine production occurs. A nephron has two main components: a renal corpuscle and a renal tubule.
Drugs gain access to the kidney via the renal artery, which progressively branches off into afferent arterioles....
1.3K
Drug Elimination by Renal Route: Glomerular Filtration01:17

Drug Elimination by Renal Route: Glomerular Filtration

7.2K
The kidney serves as the primary organ responsible for eliminating drugs and their metabolites from the body. This process, known as renal elimination, starts with glomerular filtration and results in urine formation. Each kidney houses millions of functional units called nephrons, where urine production takes place. A nephron has two main components: a renal corpuscle and a renal tubule. Drugs gain access to the kidney via the renal artery, which progressively branches off into afferent...
7.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Herbal Medications Used to Ameliorate Cardiac Conditions.

The Nursing clinics of North America·2021
Same author

Herbal Medication to Enhance or Modulate Viral Infections.

The Nursing clinics of North America·2021
Same author

Gastrointestinal Traumatic Injuries: Gastrointestinal Perforation.

Critical care nursing clinics of North America·2018
Same author

Orthopedic Injuries: Protocols to Prevent and Manage Patient Falls.

The Nursing clinics of North America·2015
Same author

Deep Brain Stimulation for Movement Disorders.

The Nursing clinics of North America·2015
Same author

Clinical Updates in Pathophysiology and Care Protocols for Nursing Management.

The Nursing clinics of North America·2015

Related Experiment Video

Updated: Feb 3, 2026

Assessment of Kidney Function in Mouse Models of Glomerular Disease
09:16

Assessment of Kidney Function in Mouse Models of Glomerular Disease

Published on: June 30, 2018

18.6K

Infection-Related Glomerular Disease.

Maria A Revell1

  • 1School of Nursing, Tennessee State University, 3500 John A. Merritt Boulevard, Campus Box 9590, Nashville, TN 37132, USA.

The Nursing Clinics of North America
|November 4, 2018
PubMed
Summary
This summary is machine-generated.

Glomerular disease, often caused by bacterial infections, requires prompt assessment and intervention. Combining medical treatment with patient education is key to preventing long-term kidney damage and promoting recovery.

Keywords:
GlomerulonephritisInfectionKidney diseaseOverfillProteinuriaUnderfill

More Related Videos

Transdermal Measurement of Glomerular Filtration Rate in Mice
07:25

Transdermal Measurement of Glomerular Filtration Rate in Mice

Published on: October 21, 2018

23.3K
Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins
09:12

Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins

Published on: January 18, 2019

10.0K

Related Experiment Videos

Last Updated: Feb 3, 2026

Assessment of Kidney Function in Mouse Models of Glomerular Disease
09:16

Assessment of Kidney Function in Mouse Models of Glomerular Disease

Published on: June 30, 2018

18.6K
Transdermal Measurement of Glomerular Filtration Rate in Mice
07:25

Transdermal Measurement of Glomerular Filtration Rate in Mice

Published on: October 21, 2018

23.3K
Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins
09:12

Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins

Published on: January 18, 2019

10.0K

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Internal Medicine

Background:

  • Glomerular disease arises from complex processes, often triggered by bacterial invasion secondary to acute or chronic illnesses.
  • Identifying the root cause of glomerular disease is crucial for effective patient management and recovery.

Purpose of the Study:

  • To emphasize the importance of early assessment and intervention in managing glomerular disease.
  • To highlight the necessity of clinician judgment in preventing chronic renal disease.
  • To advocate for a combined approach of medicinal intervention and patient education for infection-related glomerular disease.

Main Methods:

  • Clinical assessment of patients presenting with symptoms suggestive of glomerular disease.
  • Diagnostic evaluation to identify underlying causes, particularly bacterial infections.
  • Review of treatment strategies including pharmacotherapy and patient counseling.

Main Results:

  • Prompt identification of causative agents, especially bacteria, is critical for successful treatment outcomes.
  • Judicious clinical management can mitigate the risk of developing persistent renal impairment.
  • Integrated therapeutic strategies incorporating medication and education yield better results.

Conclusions:

  • Early and accurate diagnosis of glomerular disease, particularly when infection-related, is paramount.
  • Effective management necessitates a combination of clinical expertise, appropriate medical treatments, and patient engagement.
  • Preventing long-term renal sequelae requires a comprehensive approach to infection-related glomerular pathology.