Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Telomeres and Telomerase

Telomeres and Telomerase

In eukaryotic DNA replication, a single-stranded DNA fragment remains at the end of a chromosome after the removal of the final primer. This section of DNA cannot be replicated in the same manner as the rest of the strand because there is no 3’ end to which the newly synthesized DNA can attach. This non-replicated fragment results in gradual loss of the chromosomal DNA during each cell duplication. Additionally, it can induce a DNA damage response by enzymes that recognize single-stranded...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Frailty assessment and therapeutic strategies for preventing functional decline in hospitalized older adults: A narrative review of current evidence and recent advances.

Medicina clinica·2026

Same author

Effects of a short-term multicomponent functional exercise program on the serum proteome: an exploratory study in hospitalized older adults.

The journals of gerontology. Series A, Biological sciences and medical sciences·2026

Same author

[The hospital as a "Trojan Horse": 75 years of inertia in the face of the fundamental principles of geriatrics].

Revista espanola de geriatria y gerontologia·2026

Same author

Effects of a short-term multicomponent functional exercise program on the serum proteome: an exploratory study in hospitalized older adults.

The journals of gerontology. Series A, Biological sciences and medical sciences·2026

Same author

[Chronicle of a scientific metamorphosis: The REGG between its print legacy and the digital forefront].

Revista espanola de geriatria y gerontologia·2026

Same author

Predicting 1-year mortality in older cancer patients: performance of G8, SPPB, and IF-VIG in the PROFIT Study.

The journals of gerontology. Series A, Biological sciences and medical sciences·2026

Search research articles

Related Experiment Video

Updated: Feb 3, 2026

Monitoring Cancer Cell Invasion and T-Cell Cytotoxicity in 3D Culture

Monitoring Cancer Cell Invasion and T-Cell Cytotoxicity in 3D Culture

Published on: June 23, 2020

[Only «potentially» inappropriate]

Marta Gutiérrez-Valencia¹, Nicolás Martínez-Velilla²

¹Servicio de Farmacia, Navarrabiomed, Universidad Pública de Navarra (UPNA), Complejo Hospitalario de Navarra (CHN), IdiSNA, Pamplona, Navarra, España.

Revista Espanola De Geriatria Y Gerontologia

|November 4, 2018

Summary

No abstract available in PubMed .

More Related Videos

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice

Published on: April 19, 2011

Author Spotlight: Enhanced Multiplex Immunofluorescent Microscopy Protocol for Neuroscience Research

Author Spotlight: Enhanced Multiplex Immunofluorescent Microscopy Protocol for Neuroscience Research

Published on: June 21, 2024

Related Experiment Videos

Last Updated: Feb 3, 2026

Monitoring Cancer Cell Invasion and T-Cell Cytotoxicity in 3D Culture

Monitoring Cancer Cell Invasion and T-Cell Cytotoxicity in 3D Culture

Published on: June 23, 2020

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice

Published on: April 19, 2011

Author Spotlight: Enhanced Multiplex Immunofluorescent Microscopy Protocol for Neuroscience Research

Author Spotlight: Enhanced Multiplex Immunofluorescent Microscopy Protocol for Neuroscience Research

Published on: June 21, 2024