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Related Concept Videos

Intrinsically Disordered Proteins02:18

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Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
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Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
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Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases
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Hematologic Disorders.

Germán Echeverry1, Allison Dalton2

  • 1Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, Cornell University, 1275 York Avenue, New York, NY 10065, USA.

Anesthesiology Clinics
|November 5, 2018
PubMed
Summary
This summary is machine-generated.

This article reviews common hematologic (blood) conditions encountered during surgery. It offers practical clinical insights for managing patients with these blood disorders in the perioperative period.

Keywords:
CoagulopathiesHemoglobinopathiesHemophiliaPerioperative anemia

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Area of Science:

  • Hematology
  • Anesthesiology
  • Perioperative Medicine

Background:

  • The hematologic system performs vital functions: oxygen transport, waste removal, pathogen defense, and hemostasis.
  • Managing hematologic disorders in the perioperative setting presents significant clinical challenges due to system complexity.

Purpose of the Study:

  • To provide a concise overview of common hematologic conditions relevant to surgical patients.
  • To offer practical clinical pearls for perioperative hematologic management.

Main Methods:

  • Review of common hematologic afflictions in surgical patients.
  • Identification of key management strategies and clinical insights.

Main Results:

  • Highlights common hematologic issues faced in the perioperative period.
  • Presents actionable clinical pearls for managing these conditions.

Conclusions:

  • Effective perioperative management of hematologic conditions requires understanding of their complexity.
  • Clinical pearls can improve patient outcomes in the setting of common hematologic disorders.