[Non-ST elevation acute coronary syndrome: CRAC register experience]
R Hakim1, C Thuaire1, C Saint-Etienne2
1Service de cardiologie, les hôpitaux de Chartres, Chartres, France.
Annales De Cardiologie Et D'Angeiologie
|November 5, 2018
Summary
Nonagenarians with non-ST elevation acute coronary syndrome (ACS) exhibit more severe coronary artery disease and worse outcomes. This study highlights the increased risks and specific characteristics of ACS in the oldest patient population.
Area of Science:
- Cardiology
- Geriatric Medicine
- Clinical Research
Background:
- Non-ST elevation acute coronary syndrome (ACS) is a critical cardiovascular event.
- Understanding the unique clinical profiles of elderly patients with ACS is essential for tailored treatment strategies.
Purpose of the Study:
- To compare clinical, angiographic, therapeutic, and prognostic features of nonagenarians (≥90 years) with non-ST elevation ACS against younger patients.
- To identify specific challenges and outcomes in the nonagenarian ACS population.
Main Methods:
- Utilized the CRAC registry (2014-2017) database from 6 catheterization laboratories.
- Selected patients with positive-troponin non-ST elevation ACS for epidemiological and procedural data.
- Analyzed antiplatelet therapy, and hospital/one-year follow-up data for patients from the 2014-2015 period.
Main Results:
- 133 nonagenarians (2.2%) were identified among 5,964 patients with non-ST elevation ACS.
- Nonagenarians had higher rates of arterial hypertension, prior coronary angioplasty, multivessel disease, and left main disease.
- Higher one-year stroke, hospital, and one-year mortality rates were observed in nonagenarians.
Conclusions:
- Nonagenarians with positive-troponin non-ST elevation ACS present with more complex coronary artery disease.
- This elderly cohort experiences a significantly poorer prognosis compared to younger individuals.
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