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Supply and demand for hemophilia treatments-Systems-based approaches to mitigate the risk

J M Stoffman1, S Jackson2, J Teitel3

  • 1Section of Pediatric Hematology/Oncology, Department of Pediatrics and Child Health, Health Sciences Centre and the University of Manitoba, ON 2017 - 675 McDermot Avenue, Winnipeg, Manitoba, R3E 0V9, Canada.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|November 5, 2018
PubMed

Treatment of hemophilia consists of replacement of the missing coagulation factor, either prophylactically or at the time of injury or bleeding. Because of the high cost of these products, which can present a barrier to care, different procurement strategies have been developed at national and regional levels. The emergence of novel therapeutic agents adds complexity to these strategies. This paper examines the benefits and challenges of these strategies, with primary reference to the Canadian context and a consideration of the concepts of value-based care.

Keywords:
Factor replacementHemophiliaRequest for proposalsTender processValue-based health care

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