Probable cutaneous loxoscelism with mild systemic symptoms: A case report from Spain

Area of Science:

• Dermatology
• Toxicology
• Arachnology

Background:

• Cutaneous loxoscelism, a condition caused by Loxosceles spider venom, can present with varied and severe skin manifestations.
• Early misdiagnosis as bacterial infections like cellulitis is common, delaying appropriate treatment.

Observation:

• A 25-year-old woman in Valencia, Spain, developed a painful, erythematous skin lesion unresponsive to antibiotics.
• The lesion evolved into a hemorrhagic blister with necrotic ulceration.
• A Loxosceles rufescens spider was identified in the patient's home environment.

Findings:

• The patient was diagnosed with probable cutaneous loxoscelism.
• Treatment involved symptomatic care, wound management, and surgical intervention.
• Complete recovery was achieved with minimal scarring.

Implications:

• This case underscores the diagnostic complexities of cutaneous loxoscelism, particularly in regions with increasing incidence.
• It emphasizes the importance of considering arachnidism in unexplained necrotic skin lesions.
• Early and accurate diagnosis is crucial for effective management and preventing complications.