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Electrophysiological Recordings from the Giant Fiber Pathway of D. melanogaster

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Giant Recurrent Sacral Chordoma.

Linkai Jing¹, Guihuai Wang²

¹School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.

World Neurosurgery

|November 5, 2018

Summary

This case study details a patient with a giant recurrent sacral chordoma, highlighting the challenges of managing aggressive tumors and their metastases despite multiple surgeries.

Keywords:

Recurrent chordoma Sacral chordoma Surgery

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Area of Science:

Oncology
Surgical Pathology

Background:

Chordomas are rare bone tumors originating from notochordal remnants.
Recurrent sacral chordomas present significant therapeutic challenges, often requiring extensive surgical intervention.

Observation:

A 65-year-old male with a history of 7 resections for sacral chordoma presented with a giant recurrent tumor and urinary incontinence.
Imaging revealed a massive gluteal mass and multiple metastatic chordomas in the pelvic cavity and gluteal subcutaneous layer.

Findings:

A 13.15 kg recurrent chordoma was resected, with histopathology confirming chordoma.
Despite initial resection, slight recurrence and significant enlargement of metastatic lesions were noted within 12 months.
Subsequent resection of metastatic chordomas was performed, with the recurrent tumor showing no visible enlargement at the last follow-up.

Implications:

This case underscores the aggressive nature of recurrent chordomas and the potential for widespread metastasis.
Management requires a multidisciplinary approach, including aggressive surgical resection and vigilant surveillance.
Further research into novel therapeutic strategies for advanced and metastatic chordoma is warranted.