ACR Appropriateness Criteria® Suspected New-Onset and Known Nonacute Heart Failure
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Published on: July 21, 2023
, Richard D White1, Jacobo Kirsch2
1The Ohio State University Wexner Medical Center, Columbus, Ohio.
Insights
Imaging is crucial for diagnosing heart failure (HF) by assessing ventricular dysfunction and classifying HF with reduced ejection fraction (HFrEF) versus HF with preserved ejection fraction (HFpEF). It also helps differentiate ischemic from non-ischemic causes of HFrEF.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Heart failure (HF) lacks a single diagnostic test, necessitating supportive diagnostic tools.
- Imaging is essential for confirming HF and assessing ventricular function.
Purpose of the Study:
- To outline the appropriate use of medical imaging in the diagnostic workup of heart failure.
- To differentiate between HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF) using imaging.
- To guide the selection of imaging modalities for determining the etiology of HFrEF.
Main Methods:
- Utilizing transthoracic echocardiography (TTE), chest radiography, and cardiac MRI for initial HF assessment and classification.
- Employing coronary computed tomography angiography (CTA) or coronary arteriography for ischemic heart disease evaluation.
- Recommending myocardial perfusion imaging (SPECT/CT, PET/CT, MRI) and myocardial contraction assessment (stress TTE, MRI) for etiological diagnosis.
Main Results:
- Resting TTE and chest radiography are appropriate for Variant 1 (HF confirmation).
- Resting TTE and/or MRI are suitable for Variant 2 (HFrEF vs. HFpEF differentiation).
- A range of advanced imaging techniques, including coronary CTA, perfusion imaging, and cardiac MRI, are appropriate for Variant 3 (HFrEF etiology).
Conclusions:
- Medical imaging is integral to the stepwise diagnosis and management of heart failure.
- Appropriate imaging selection aids in classifying HF and identifying its underlying causes.
- The American College of Radiology Appropriateness Criteria provide evidence-based guidelines for optimal imaging utilization in HF.
Abstract:
While there is no single diagnostic test for heart failure (HF), imaging plays a supportive role beginning with confirmation of HF, especially by detecting ventricular dysfunction (Variant 1). Ejection fraction (EF) is important in HF classification, and imaging plays a subsequent role in differentiation between HF with reduced EF (HFrEF) versus preserved EF (HFpEF) (Variant 2). Once HFrEF is identified, distinction between ischemic and nonischemic etiologies with imaging support (Variant 3) facilitates further planning. Imaging approaches which are usually appropriate include: both resting transthoracic echocardiography (TTE) and chest radiography for Variant 1; resting TTE and/or MRI (including functional, without absolute need for contrast) for Variant 2; and for Variant 3, a. Coronary CTA or coronary arteriography (if high pretest probability/symptoms for ischemic disease) for coronary assessment; b. Rest/vasodilator stress SPECT/CT, PET/CT, or MRI for myocardial perfusion assessment; c. Rest/exercise or inotropic stress TTE for myocardial contraction assessment; or d. MRI (including morphologic with contrast) for myocardial characterization. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
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