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Cataract quantification using swept-source optical coherence tomography.

João E G Brás1, Wolfgang Sickenberger1, Nino Hirnschall1

  • 1From the SciTec Department (Brás, Sickenberger), JenVis Research GbR, Ernst-Abbe-Hochschule Jena, Jena, Germany Vienna Institute for Research in Ocular Surgery (Hirnschall, Findl), Ophthalmology Department, Hanusch-Hospital, Vienna, Austria.

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Summary
This summary is machine-generated.

This study developed an objective method to quantify cataract density using swept-source optical coherence tomography (SS-OCT). The SS-OCT system showed good correlation with traditional grading, offering a new tool for cataract assessment.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Cataract quantification traditionally relies on subjective grading systems like Lens Opacities Classification System II (LOCS II).
  • Objective and reproducible methods are needed for accurate cataract assessment and management.

Purpose of the Study:

  • To develop and validate an objective cataract quantification method using a swept-source optical coherence tomography (SS-OCT) device.
  • To correlate SS-OCT measurements with established clinical grading and surgical outcomes.

Main Methods:

  • A prospective multicenter case series involving patients with cataracts.
  • Two independent examiners performed LOCS II grading; SS-OCT scans were analyzed to develop an objective cataract quantification system.
  • Phacoemulsification energy, time, visual acuity, and contrast sensitivity were recorded for correlation analysis.

Main Results:

  • The study included 186 eyes from 113 patients. Inter-examiner agreement for LOCS II grading was high (0.91).
  • The SS-OCT-based system showed strong correlations with LOCS II grading (0.86 and 0.76).
  • OCT-based scores significantly correlated with phacoemulsification time (0.71) and energy (0.64).

Conclusions:

  • Swept-source OCT enables objective quantification and documentation of cataract density.
  • The developed SS-OCT system provides values that correlate well with the conventional LOCS II classification.
  • This technology offers a promising tool for standardized cataract assessment.