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Updated: Feb 3, 2026

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma
Published on: April 15, 2022
Bone marrow transplant and pediatric multiple myeloma
Kimberly A Davidow1, Andrew W Walter2, E Anders Kolb2
1Department of Pediatrics, Nemours/Alfred I. duPont Hospital for Children at Thomas Jefferson University, Wilmington, Delaware.
Pediatric multiple myeloma is rare, but this report details two adolescent cases. Treatments included stem cell transplants, offering insights into managing this uncommon malignancy in young patients.
Area of Science:
- Hematology
- Pediatric Oncology
- Cancer Research
Background:
- Multiple myeloma is a plasma cell malignancy, rarely diagnosed in individuals under 30.
- Pediatric multiple myeloma accounts for a small fraction of all multiple myeloma cases.
Observation:
- This report focuses on two adolescent patients diagnosed with multiple myeloma between ages 12 and 16.
- The cases highlight the occurrence of this rare cancer in a pediatric demographic.
Findings:
- The study details the specific treatment regimens employed for these young patients.
- Treatment strategies incorporated both autologous and allogeneic stem cell transplantation.
Implications:
- These cases contribute valuable clinical data on managing pediatric multiple myeloma.
- Understanding treatment outcomes in adolescents can inform future therapeutic approaches for rare childhood cancers.
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Published on: January 7, 2019
09:41An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
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