Related Experiment Video
Updated: Feb 3, 2026

Analyzing Gene Expression from Marine Microbial Communities using Environmental Transcriptomics
Published on: February 18, 2009
Terretonin D1, a new meroterpenoid from marine-derived Aspergillus terreus ML-44
Chang-Jing Wu1, Xiang Cui1, Biao Xiong2
1a Institute of Neuroscience and Translational Medicine, College of Life Science and Agronomy , Zhoukou Normal University , Zhoukou , China.
Abstract:
A new meroterpenoid, named terretonin D1 (1), and three known ones, terretonin (2), terretonin A (3), and terretonin D (4), were isolated from marine-derived fungus Aspergillus terreus ML-44. The structure of 1 was elucidated by extensive spectroscopic methods, including 1D and 2D NMR, HR-ESI-MS, and the absolute configuration was determined by X-ray crystallographic analysis. The anti-inflammation activity of 1-4 was preliminarily tested, and all of them weakly inhibited the nitric oxide (NO) production of RAW264.7 macrophages stimulated by lipopolysaccharide (LPS), with inhibitory rates of 22-34% at 50 μg/mL.
Related Concept Videos
Measurement: Derived Units
Higher Derivatives
Derivatives
The Derivative as a Function
Derivatives: Problem Solving
First Derivative Test: Problem Solving

