Related Experiment Video
Updated: Feb 3, 2026

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
Published on: March 8, 2024
Alveolar ridge preservation using an open membrane approach for sockets with bone deficiency: A randomized controlled
Dong-Joo Sun1, Hyun-Chang Lim2, Dong-Woon Lee1
1Department of Periodontology, Veterans Health Service Medical Center, Seoul, Republic of Korea.
Background:
Various approaches are used for alveolar ridge preservation (ARP); however, there is no standard method or material.
Purpose:
To investigate the effect of ARP with a dense polytetrafluoroethylene (d-PTFE) membrane and freeze-dried irradiated allogenic bone for sockets with bone deficiency.
Materials And Methods:
Thirty-four patients (with sockets exhibiting ≥3 mm hard tissue loss in ≥1 walls) were randomized to undergo natural socket healing (control) or ARP with a d-PTFE membrane and freeze-dried irradiated allogenic bone (test group). After 4 months, horizontal and vertical ridge changes were measured using cone beam computed tomography.
Results:
Ridge width at l mm below the ridge crest demonstrated significantly less change in the test group (median =2.3; Q1 = 0.6; Q3 = 4.3 mm) than in the control group (median =3.9; Q1 =2.6; Q3 = 7.8 mm; P = .021). There was no significant difference between the two groups in horizontal ridge changes at 3 and 5 mm below the crest or vertical changes (P > .05). Requirement for bone augmentation at implant placement was significantly reduced in the test group compared to the control group (P < .001).
Conclusion:
ARP with a d-PTFE membrane and freeze-dried irradiated allogenic bone substitute reduced horizontal bone resorption in sockets with bone deficiency.
Related Concept Videos
Clinical Trials
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview
Statistical Software for Data Analysis and Clinical Trials
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Alveoli and Alveolar Ducts
Trial and Error and Algorithm

