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Updated: Feb 3, 2026

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Fluorescence Angiography for Evaluation of Aneurysm Perfusion and Parent Artery Patency in Rat and Rabbit Aneurysm Models
Published on: July 24, 2019
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Persistent hypoglossal artery aneurysm: Case report and qualitative systematic review
George H Tse1, Andrew Martin1, Richard A Dyde1
1Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield, UK.
Summary
This study reports the first endovascular treatment of a ruptured aneurysm associated with a persistent hypoglossal artery in an elderly patient. This approach offers a safe and effective alternative to surgery for such rare intracranial aneurysms.
Area of Science:
- Neuroscience
- Vascular Surgery
- Medical Imaging
Background:
- Persistent hypoglossal artery is a common developmental anomaly.
- Intracranial aneurysms require prompt treatment, with endovascular coiling being a standard approach.
- Data on treating aneurysms associated with persistent hypoglossal arteries is scarce due to low incidence.
Observation:
- A case report of the oldest patient treated for a persistent hypoglossal artery-associated aneurysm.
- The aneurysm originated at the posterior inferior cerebellar artery.
- Endovascular treatment was successfully performed via the persistent hypoglossal artery.
Findings:
- This case represents the first reported endovascular treatment of a persistent hypoglossal artery aneurysm.
- Endovascular therapy is a safe and effective treatment option for ruptured posterior inferior cerebellar artery aneurysms arising from a persistent hypoglossal artery.
- A qualitative review of literature indicates a predominance of surgical interventions for similar cases.
Implications:
- Endovascular treatment should be considered for persistent hypoglossal artery aneurysms, particularly when arising from the posterior inferior cerebellar artery.
- This case expands treatment options for rare cerebrovascular pathologies.
- Further case studies and literature reviews are needed to solidify evidence for endovascular approaches.
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